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Late Breakers

Top 5 Industry Updates

Tralokinumab Shows Consistent Efficacy in Atopic Dermatitis Regardless of Coexisting Atopic Conditions

post hoc analysis of ECZTRA trials finds tralokinumab effective and well-tolerated for moderate-to-severe atopic dermatitis, even in patients with asthma, food allergy, or allergic rhinitis.

No Postoperative Pancreatic Fistula Outcomes Difference Between Blumgart and Pancreatogastrostomy Anastomosis

A new study reports that postoperative pancreatic fistula outcomes after pancreatogastrostomy do not differ between patients undergoing Blumgart anastomosis and pancreatogastrostomy anastomosis; however, the latter leads to better postoperative quality of life

Industry Information

DUPIXENT® (dupilumab) APPROVED FOR AN 8th INDICATION

Learn about the new approval for DUPIXENT

Novel Risk Score Predicts Post-transplant Recurrence in Perihilar Cholangiocarcinoma

A new study documents the validation and application of a risk score for predicting post-transplant recurrence in perihilar cholangiocarcinoma.

Industry Information

New Data Show 40-Gene Expression Profile (DecisionDx®-SCC) Identifies Cutaneous Squamous Cell Carcinoma Patients Most Likely to Benefit from Adjuvant Radiation Therapy

Study results demonstrate that DecisionDx-SCC can identify high-risk cutaneous squamous cell carcinoma patients who are most likely to benefit from adjuvant radiation therapy.

Subcutaneous Versus Combined Subcutaneous and Intramuscular Botulinum Toxin for Androgenetic Alopecia

A randomized trial finds that botulinum toxin A, whether administered subcutaneously or via combined subcutaneous and intramuscular injection, shows no meaningful improvement in hair growth outcomes in men with androgenetic alopecia.

Self-directed Sensor-based mHealth Exercise Intervention Superior to Usual Care in Knee OA

A new study confirms the superiority of a mobile health exercise intervention for pain reduction in knee osteoarthritis.

Risk Levels for Hematologic, Solid Organ Cancers Increased Among Systemic Sclerosis Patients

A new study reports that the risks for both hematologic and solid organ cancers are significantly increased among patients with systemic sclerosis, with variation according to auto-antibody status.

Hot Endoscopic Mucosal Resection Better Minimizes Recurrence of Large Colorectal Polyps

A new study concludes that cold endoscopic mucosal resection (EMR) results in a greater recurrence rate without a significant difference in severe adverse events versus hot EMR.

Multistrain Probiotics Enhance Functional Ability in OA Patients

A new study concludes that a multistrain probiotic improves functional ability in osteoarthritis.

200 mg of Simethicone Best for Afternoon Colonoscopy

A new study suggests that optimal dose for simethicone for afternoon colonoscopy.

Sonelokimab Therapy Improves Signs and Symptoms of PsA in Phase 2 Trial

A new study confirms the potential of sonelokimab (SLK) for treatment of psoriatic arthritis.

Clinical Management of Pigmented Purpuric Dermatoses: Insights from a Nationwide Dermatology Survey in Italy

A multicenter survey among Italian dermatologists highlights real-world management patterns for pigmented purpuric dermatoses, revealing reliance on topical corticosteroids and moisturizers as first-line therapies and underscoring the need for standardized treatment guidelines.

Subtyping Intestinal Metaplasia May Predict Gastric Cancer Risk

A new study supports the utility of subtyping intestinal metaplasia as a predictor of gastric cancer risk.

Causal Relationship Confirmed Between Hypertension and Gout Risk, without Link Confirmed with Anti-hypertensive Medications

A new study eports a causal link between the risk of gout and hypertension but could not confirm a connection with three anti-hypertensive medications.

Benefits of Dual Hypothermic Oxygenated Machine Perfusion in Donation After Circulatory Death LT Last for Up to Five Years

A new study reports that the benefits of dual hypothermic oxygenated machine perfusion in donation after circulatory death liver transplantation persist for up to 5 years.

GLP-1 Receptor Agonists Emerge as Potential Modulators of Inflammation and Angiogenesis in Wound Healing

New evidence suggests that GLP-1 receptor agonists may be promising adjunctive therapies for chronic diabetic wound healing.

Adding Sintilimab to Capecitabine–Oxaliplatin Following Radiotherapy Improves the LARC Response Rate

A new study reports that adding sintilimab to capecitabine–oxaliplatin following radiotherapy improves the pathological complete response rate in patients with locally advanced rectal cancer, albeit with more postoperative complications.

Blood-based Test Shows "Acceptable" Accuracy for Colorectal Cancer Detection

A new study reports that a blood-based test demonstrated acceptable accuracy for colorectal cancer detection, although its detection of advanced precancerous lesions remains inadequate.

Chronic Hand Eczema: Key Clinical Questions and Practical Insights from the EADV Contact Dermatitis Task Force

A new consensus review from the EADV Contact Dermatitis Task Force addresses the pathogenesis, diagnosis, and evolving treatment landscape of chronic hand eczema.

Combining Electrical Muscle Stimulation with Blood Flow Restriction Training Can Increase Muscle Strength in Knee OA

A new study found that combining blood flow restriction training with electrical muscle stimulation improves muscle strength in football players with knee osteoarthritis.

New Imaging-based Tool Predicts Early Progression to Atezolizumab plus Bevacizumab Therapy in Advanced HCC

A new study reports on the development and use of a new imaging-based tool to predict early progression to atezolizumab plus bevacizumab therapy in advanced hepatocellular carcinoma.

Real-World Insights Into Topical Ruxolitinib for Vitiligo from Patient-Reported Experiences

A novel infodemiology analysis of nearly 3,000 Reddit posts reveals real-world patterns of efficacy, side effects, and access barriers associated with topical ruxolitinib for vitiligo.

Current Liver Stiffness Measurement Optimal for Predicting First Hepatic Decompensation in Patients with Discordant Prior Measurements

A new study concludes that referring to the current liver stiffness measurement is best when estimating first hepatic decompensation.

Metabolic Response to Mediterranean Diet Shows Inverse Association with RA Risk

A new study concludes that the metabolic response to the Mediterranean diet is inversely associated with the risk of rheumatoid arthritis.

Two-sample Fecal Immunochemical Testing Identifies Patients at High Risk for Colorectal Cancer

A new study concludes that the systemic immune–inflammation index and systemic inflammation response index both demonstrate relationships with osteoarthritis.

Early Phase Studies Confirm Favorable PK and Safety of Clascoterone Cream 1% in Acne Treatment

Five phase 1 clinical studies demonstrate that clascoterone cream 1% offers low systemic absorption, minimal irritation, and a strong safety profile, supporting its use as a topical androgen receptor inhibitor for acne vulgaris.

Ripretinib May Benefit Patients with Gastrointestinal Stromal Tumors Intolerant to Sunitinib

A new study suggests that patients with advanced gastrointestinal stromal tumors who experience disease progression on imatinib and sunitinib intolerance could be treated with ripretinib.

Neutrophil Percentage-to-Albumin Ratio Independently Predicts Risk of Developing RA-Related Osteoporosis

A new study concludes that the neutrophil percentage-to-albumin ratio independently predicts the risk of developing osteoporosis in rheumatoid arthritis.

TACE Combined with Atezolizumab and Bevacizumab Safe, Feasible for Intermediate-Stage HCC

A new study reports that transarterial chemoembolization combined with atezolizumab and bevacizumab appears safe and feasible for intermediate-stage hepatocellular carcinoma.

No Survival Benefit Difference in MaB + Chemo vs. Chemo Alone in Gastric Cancer Patients with Low PD-L1 Expression

A new study has determined that the monoclonal antibodies to chemotherapy does not alter the survival benefit among patients with gastric cancer and low programmed death-ligand 1 expression.

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Late Breakers

Top 5 Industry Updates

Tralokinumab Shows Consistent Efficacy in Atopic Dermatitis Regardless of Coexisting Atopic Conditions

No Postoperative Pancreatic Fistula Outcomes Difference Between Blumgart and Pancreatogastrostomy Anastomosis

Industry Information

DUPIXENT® (dupilumab) APPROVED FOR AN 8th INDICATION

Novel Risk Score Predicts Post-transplant Recurrence in Perihilar Cholangiocarcinoma

Industry Information

New Data Show 40-Gene Expression Profile (DecisionDx®-SCC) Identifies Cutaneous Squamous Cell Carcinoma Patients Most Likely to Benefit from Adjuvant Radiation Therapy

Subcutaneous Versus Combined Subcutaneous and Intramuscular Botulinum Toxin for Androgenetic Alopecia

Read More

Self-directed Sensor-based mHealth Exercise Intervention Superior to Usual Care in Knee OA

Risk Levels for Hematologic, Solid Organ Cancers Increased Among Systemic Sclerosis Patients

Hot Endoscopic Mucosal Resection Better Minimizes Recurrence of Large Colorectal Polyps

Multistrain Probiotics Enhance Functional Ability in OA Patients

200 mg of Simethicone Best for Afternoon Colonoscopy

Sonelokimab Therapy Improves Signs and Symptoms of PsA in Phase 2 Trial

Clinical Management of Pigmented Purpuric Dermatoses: Insights from a Nationwide Dermatology Survey in Italy

Subtyping Intestinal Metaplasia May Predict Gastric Cancer Risk

Causal Relationship Confirmed Between Hypertension and Gout Risk, without Link Confirmed with Anti-hypertensive Medications

Benefits of Dual Hypothermic Oxygenated Machine Perfusion in Donation After Circulatory Death LT Last for Up to Five Years

GLP-1 Receptor Agonists Emerge as Potential Modulators of Inflammation and Angiogenesis in Wound Healing

Adding Sintilimab to Capecitabine–Oxaliplatin Following Radiotherapy Improves the LARC Response Rate

Blood-based Test Shows "Acceptable" Accuracy for Colorectal Cancer Detection

Chronic Hand Eczema: Key Clinical Questions and Practical Insights from the EADV Contact Dermatitis Task Force

Combining Electrical Muscle Stimulation with Blood Flow Restriction Training Can Increase Muscle Strength in Knee OA

New Imaging-based Tool Predicts Early Progression to Atezolizumab plus Bevacizumab Therapy in Advanced HCC

Real-World Insights Into Topical Ruxolitinib for Vitiligo from Patient-Reported Experiences

Current Liver Stiffness Measurement Optimal for Predicting First Hepatic Decompensation in Patients with Discordant Prior Measurements

Metabolic Response to Mediterranean Diet Shows Inverse Association with RA Risk

Two-sample Fecal Immunochemical Testing Identifies Patients at High Risk for Colorectal Cancer

Early Phase Studies Confirm Favorable PK and Safety of Clascoterone Cream 1% in Acne Treatment

Ripretinib May Benefit Patients with Gastrointestinal Stromal Tumors Intolerant to Sunitinib

Neutrophil Percentage-to-Albumin Ratio Independently Predicts Risk of Developing RA-Related Osteoporosis

TACE Combined with Atezolizumab and Bevacizumab Safe, Feasible for Intermediate-Stage HCC

No Survival Benefit Difference in MaB + Chemo vs. Chemo Alone in Gastric Cancer Patients with Low PD-L1 Expression