Dapsone Gel, 7.5%
Brand and Other Names:
ACZONE
Mechanism of Action:
The mechanism of action of dapsone gel in treating acne vulgaris is not known.
Indications:
ACZONE® Gel, 7.5%, is a sulfone indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.
Route:
Topical
Dose:
- Apply once daily.
- Apply approximately a pea-sized amount of ACZONE Gel, 7.5%, in a thin layer to the entire face. A thin layer can also be applied to other affected areas.
- If there is no improvement after 12 weeks, treatment with ACZONE Gel, 7.5% should be reassessed.
- For topical use only. Not for oral, ophthalmic, or intravaginal use.
Adverse Reactions:
Most common (incidence ≥ 0.9%) adverse reactions are application site dryness and pruritus.
Contraindication:
None
Warnings and Precautions:
- Methemoglobinemia: Cases of methemoglobinemia have been reported. Discontinue ACZONE Gel if signs of methemoglobinemia occur.
- Hemolysis: Some patients with Glucose-6-phosphate Dehydrogenase (G6PD) deficiency using topical dapsone developed laboratory changes suggestive of hemolysis.
See package insert for full prescribing information.