fluticasone propionate
The precise mechanism through which fluticasone propionate affects allergic rhinitis symptoms is not known.
Azelastine hydrochloride and fluticasone propionate nasal spray is indicated for the relief of symptoms of seasonal allergic rhinitis in adult and pediatric patients 6 years of age and older.
Nasal spray: 137 mcg of azelastine hydrochloride and 50 mcg of fluticasone propionate per spray.
Somnolence. Local nasal effects, including epistaxis, nasal ulceration, nasal septal perforation, impaired wound healing, and Candida albicans infection. Glaucoma and Cataracts. Immunosuppression and Risk of Infections. Hypercorticism and Adrenal Suppression, including growth reduction.
Azelastine hydrochloride and fluticasone propionate nasal spray is contraindicated in patients with hypersensitivity to azelastine hydrochloride, fluticasone propionate, or to any other ingredients of azelastine hydrochloride and fluticasone propionate nasal spray. Reactions have included anaphylaxis.
Somnolence, Local Nasal Effects, Glaucoma and Cataracts, Immunosuppression and Risk of Infections, Hypercorticism and Adrenal Suppression, Use of Cytochrome P450 3A4 Inhibitors, Effect on Growth
Azelastine hydrochloride and fluticasone propionate nasal spray is formulated as a white, uniform metered-spray suspension for nasal administration. It is a fixed dose combination product containing an antihistamine (H1 receptor antagonist) and a corticosteroid as active ingredients.