Mirtazapine
Brand and Other Names:
Remeron
Mechanism of Action:
The mechanism of action of REMERON® (mirtazapine) Tablets, as with other drugs effective in the treatment of major depressive disorder, is unknown.
Indications:
REMERON® (mirtazapine) Tablets are indicated for the treatment of major depressive disorder.
Route:
Oral
Dose:
The recommended starting dose for REMERON® (mirtazapine) Tablets is 15 mg/day, administered in a single dose, preferably in the evening prior to sleep.
Adverse Reactions:
The following adverse reactions are described in more detail in other sections of the prescribing information: Hypersensitivity, Suicidal Thoughts and Behaviors, Agranulocytosis, Serotonin Syndrome, Angle-Closure Glaucoma, Drug Reaction with Eosinophilia and Systemic Symptoms (DRES)
Increased Appetite and Weight Gain, Somnolence, Activation of Mania or Hypomania, Seizures, Elevated Cholesterol and Triglycerides, Hyponatremia, Transaminase Elevations, Discontinuation Syndrome, and Use in Patients with Concomitant Illness. (See Full Prescribing Information.)
Contraindication:
REMERON® (mirtazapine) Tablets are contraindicated in patients with a known hypersensitivity to mirtazapine or to any of the excipients. Monoamine Oxidase Inhibitors: The concomitant use of REMERON Tablets and a monoamine oxidase (MAO) inhibitor is contraindicated. REMERON should not be used within 14 days of initiating or discontinuing therapy with a monoamine oxidase inhibitor (MAOI).
Warnings and Precautions:
Dizziness, abnormal dreams, sensory disturbances (including paresthesia and electric shock sensations), agitation, anxiety, fatigue, confusion, headache, tremor, nausea, vomiting, and sweating, or other symptoms which may be of clinical significance. (See Full Prescribing Information.)
See package insert for full prescribing information.