prednisolone acetate
Glucocorticoids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.
Used to treat steroid-responsive inflammation of:
- Palpebral and bulbar conjunctiva
- Cornea
- Anterior segment of the globe
1–2 drops into the conjunctival sac 2–4 times daily
Common:
- Elevated IOP
- Cataract formation
- Delayed healing
Less common:
- Infections (bacterial, fungal, viral)
- Ocular irritation (burning, stinging, blurry vision)
- Allergic reactions, eye pain, pruritus
- Rare: uveitis, optic nerve damage, corneal ulcers, mydriasis, ptosis
Active untreated purulent ocular infections
Most viral eye diseases (e.g., herpes simplex, vaccinia, varicella)
Mycobacterial or fungal eye infections
Known hypersensitivity to ingredients or corticosteroids
Prolonged use risks:
- Posterior subcapsular cataracts
- Elevated intraocular pressure → glaucoma
- Suppressed immune response → secondary infections
- Delayed wound healing, especially post-cataract surgery
Use with caution in glaucoma, herpes simplex history, or thin corneal/scleral tissue
Contains sodium bisulfite, a potential allergen (especially in asthmatics)