Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states.

PredniSONE Tablets are indicated in the following conditions: Endocrine Disorders, Rheumatic Disorders, Collagen Diseases, Dermatologic Diseases, Allergic States, Ophthalmic Diseases, Respiratory Diseases, Hematologic Disorders, Neoplastic Diseases, Edematous States, Gastrointestinal Diseases, and Miscellaneous (See Full Prescribing Information.)

The initial dosage of PredniSONE Tablets may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated.

The following adverse reactions have been reported with prednisone or other corticosteroids: anaphylactoid or hypersensitivity reactions, anaphylaxis, angioedema, bradycardia, Cardiovascular System, Dermatologic, Endocrine, Fluid and Electrolyte Disturbances, Gastrointestinal, Hematologic, Metabolic, Musculoskeletal, Neurological/Psychiatric, Ophthalmic, and other (See Full Prescribing Information.)

Prednisone tablets are contraindicated in systemic fungal infections and known hypersensitivity to components.

Kaposi’s sarcoma has been reported to occur in patients receiving corticosteroid therapy, most often for chronic conditions.