ertapenem
Ertapenem sodium is a carbapenem antibiotic
Ertapenem is a penem-class antibiotic approved for use in adults and pediatric patients (≥3 months). It's indicated for treating moderate to severe infections caused by susceptible bacteria.
Adults: 1 g once daily (IV/IM)
Children (3 months – 12 years): 15 mg/kg twice daily (max 1 g/day)
Diarrhea
Nausea
Headache
Infusion site complications
Known hypersensitivity to beta-lactams or components of the formulation
IM use is contraindicated in patients allergic to amide-type local anesthetics (e.g., lidocaine)
Severe hypersensitivity reactions, including anaphylaxis
Seizure risk, especially in those with CNS disorders or renal impairment
Interaction with valproic acid/divalproex may lower serum levels, increasing seizure risk
C. difficile-associated diarrhea: Can range from mild to life-threatening
Drug-resistant bacteria: Avoid inappropriate or prolonged use