Hylan G-F 20 is a viscosupplementation treatment, specifically Synvisc or Synvisc-One, used to manage knee pain associated with osteoarthritis. It's an intra-articular injection, meaning it's injected directly into the knee joint. Hylan G-F 20 is a hyaluronan derivative, similar to a substance naturally found in joints, and works by acting as a lubricant and shock absorber to improve joint movement and reduce pain.

Here's a more detailed explanation:

What it is: Hylan G-F 20 is a viscosupplement, meaning it's a substance that adds to the natural fluid in the joint to improve its lubricating and shock-absorbing properties. It is a hyaluronan derivative, meaning it's a modified form of a substance found naturally in the body's joints.

How it works: The hyaluronan in Hylan G-F 20 helps to reduce friction and cushion the knee joint, which can alleviate pain and improve mobility. It essentially acts as a lubricant and shock absorber within the joint.

When it's used: It's typically used for patients with osteoarthritis of the knee who haven't found sufficient relief from conservative treatments like physical therapy or pain relievers like acetaminophen. Synvisc is administered as a series of injections, while Synvisc-One is a single larger injection.

Important Considerations:

Contraindications:

Hylan G-F 20 is contraindicated for patients with known hypersensitivity to hyaluronan products or infections in or around the knee.
Side Effects:

While generally safe, side effects can include allergic reactions, joint pain, swelling, and difficulty breathing. It's important to report any unusual symptoms to a healthcare professional.
Not a Cure:

It's important to note that Hylan G-F 20 is not a cure for osteoarthritis, but it can be an effective way to manage pain and improve function.

See package insert for full prescribing information.

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Hylan G-F 20