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Common Skin Disorders of GI Disease

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Tina Bhutani, MD, MAS, FAAD Director, Dermatology Clinical Research Unit, University of California, San Francisco

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Common Skin Disorders of GI Disease - Case 1

Case Study thumbnail 131

Common Skin Disorders of GI Disease - Case 2

1. A 21-year-old male with a history of celiac disease presents with an intensely itchy rash on his elbows and knees. A biopsy reveals subepidermal vesiculation with numerous neutrophils. What is the most likely diagnosis?

Select only 1 answer.

  1. A. Psoriasis
  2. B. Dermatitis Herpetiformis
  3. C. Erythema Nodosum
  4. D. Hidradenitis Suppurativa

2. Which skin condition is most commonly associated with inflammatory bowel disease (IBD)?

Select only 1 answer.

  1. A. Psoriasis
  2. B. Erythema Nodosum
  3. C. Sweet’s Syndrome
  4. D. Hidradenitis Suppurativa

3. A 28-year-old female presents with painful, deep-seated nodules in her axillae and groin. She reports that these nodules often progress to abscesses and drain foul-smelling discharge. What is the most likely diagnosis?

Select only 1 answer.

  1. A. Psoriasis
  2. B. Dermatitis Herpetiformis
  3. C. Hidradenitis Suppurativa
  4. D. Erythema Nodosum

4. Which of the following is a classic sign of pancreatic cancer metastasis to the skin?

Select only 1 answer.

  1. A. Sweet’s Syndrome
  2. B. Sister Mary Joseph Nodule
  3. C. Pyoderma Gangrenosum
  4. D. Hidradenitis Suppurativa

5. Which skin finding is most commonly associated with hepatitis C?

Select only 1 answer.

  1. A. Erythema Nodosum
  2. B. Porphyria Cutanea Tarda
  3. C. Psoriasis
  4. D. Hidradenitis Suppurativa

6. A 30-year-old female with Crohn’s disease develops a painful ulcer with necrotic undermined borders on her leg. What is the most likely diagnosis?

Select only 1 answer.

  1. A. Erythema Nodosum
  2. B. Dermatitis Herpetiformis
  3. C. Pyoderma Gangrenosum
  4. D. Sweet’s Syndrome

7. Which skin manifestation is commonly seen in patients with liver cirrhosis?

Select only 1 answer.

  1. A. Hidradenitis Suppurativa
  2. B. Dermatitis Herpetiformis
  3. C. Spider Angiomas
  4. D. Sweet’s Syndrome

8. Which of the following is a classic histological finding in Sweet’s Syndrome?

Select only 1 answer.

  1. A. Granular IgA along the basement membrane
  2. B. Septal panniculitis without vasculitis
  3. C. Dense neutrophilic infiltrate in the dermis
  4. D. Subepidermal vesiculation

9. Which condition is characterized by painful oral ulcers and is often associated with IBD activity?

Select only 1 answer.

  1. A. Pyoderma Gangrenosum
  2. B. Oral Aphthous Stomatitis
  3. C. Sweet’s Syndrome
  4. D. Hidradenitis Suppurativa

10. Which condition can present as a paradoxical skin reaction in patients treated with TNF-alpha inhibitors?

Select only 1 answer.

  1. A. Dermatitis Herpetiformis
  2. B. Psoriasis
  3. C. Erythema Nodosum
  4. D. Sweet’s Syndrome

11. Which skin condition is known for presenting with painful red nodules on the shins without ulceration?

Select only 1 answer.

  1. A. Pyoderma Gangrenosum
  2. B. Sweet’s Syndrome
  3. C. Hidradenitis Suppurativa
  4. D. Erythema Nodosum

12. Which skin finding is commonly seen in patients with primary biliary cirrhosis?

Select only 1 answer.

  1. A. Xanthelasmas
  2. B. Hidradenitis Suppurativa
  3. C. Sweet’s Syndrome
  4. D. Pyoderma Gangrenosum