Takayasu's Arteritis and Polyarteritis Nodosa
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Polyarteritis Nodosa - Case 1
Takayasu's Arteritis - Case 1
Polyarteritis Nodosa - Case 2
Takayasu's Arteritis - Case 2
Takayasu's Arteritis - Basic Level Case Study
Polyarteritis Nodosa (PAN) - Intermediate Level Case Study
Takayasu's Arteritis - Advanced Level Case Study
1. Which imaging modality is recommended for diagnosing and monitoring Takayasu’s arteritis (TAK)?
Select only 1 answer.
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A. Conventional angiogram
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B. MRA
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C. PET scan
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D. Radiographic bone scan
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E. CT angiography
2. What are the hallmark histopathological features of Polyarteritis Nodosa (PAN)?
Select only 1 answer.
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A. Granulomatous inflammation and giant cells
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B. Transmural inflammation and fibrinoid necrosis
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C. Intimal hyperplasia and foam cells
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D. Lymphocytic infiltration and necrotizing granulomas
3. Which of the following clinical features is highly suggestive of Takayasu’s arteritis (TAK)?
Select only 1 answer.
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A. Livedo reticularis
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B. Bruit over the left subclavian artery
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C. Red blood cell cast on urinalysis
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D. A positive ANA
4. What is the most appropriate initial pharmacologic management for a patient with newly diagnosed severe active Takayasu’s arteritis?
Select only 1 answer.
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A. Low-dose glucocorticoids
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B. High-dose oral glucocorticoids
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C. Methotrexate alone
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D. Surgical intervention
5. In patients with Polyarteritis Nodosa (PAN) and peripheral neuropathy, what is the recommended biopsy technique for diagnosis?
Select only 1 answer.
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A. Skin biopsy alone
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B. Nerve biopsy alone
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C. Muscle biopsy alone
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D. Combined nerve and muscle biopsy
6. Which of the following statements about the epidemiology of Takayasu’s arteritis (TAK) is correct?
Select only 1 answer.
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A. It predominantly affects elderly males of European descent.
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B. It predominantly affects young females of Asian descent
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C. It has a higher incidence in African American populations.
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D. It is equally common in males and females of all ages
7. What are the potential clinical manifestations of Polyarteritis Nodosa (PAN) due to mesenteric artery involvement?
Select only 1 answer.
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A. Intermittent claudication
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B. Bilateral vision loss
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C. Postprandial abdominal pain
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D. Chronic cough
8. Which clinical feature differentiates Takayasu’s arteritis from Giant Cell Arteritis?
Select only 1 answer.
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A. Jaw claudication
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B. Limb claudication
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C. Temporal artery tenderness
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D. Scalp tenderness
9. What is the role of PET scans in the management of Takayasu’s arteritis (TAK)?
Select only 1 answer.
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A. They are the first-line diagnostic tool for TAK.
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B. They assess metabolic activity and inflammation before damage occurs.
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C. They replace the need for MRAs in TAK management.
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D. They are primarily used for evaluating bone involvement in TAK.
10. Which of the following clinical features is NOT typically associated with Polyarteritis Nodosa (PAN)?
Select only 1 answer.
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A. Hypertension
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B. Mononeuritis multiplex
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C. Livedo reticularis
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D. Cranial nerve palsy
11. What is the most common site of early lesions in Takayasu’s arteritis (TAK)?
Select only 1 answer.
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A. Right renal artery
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B. Left proximal subclavian artery
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C. Abdominal aorta
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D. Common iliac arteries
12. Which of the following statements about the pathogenesis of Takayasu’s arteritis (TAK) is correct?
Select only 1 answer.
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A. It involves primarily B cells and autoantibodies.
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B. It is characterized by granulomatous inflammation and infiltrating T cells.
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C. It is triggered by bacterial infections.
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D. It predominantly affects the venous system.
13. Which of the following is a severe complication of untreated Polyarteritis Nodosa (PAN)?
Select only 1 answer.
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A. Temporal arteritis
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B. Pulmonary fibrosis
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C. Mesenteric ischemia
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D. Retinal detachment